transdermal topical supplements

A transdermal supplement is a type of product that delivers active ingredients through the skin and directly into the bloodstream. Transdermal supplements can come in various forms, such as patches, gels, creams, or sprays. This method of administration bypasses the digestive system, allowing for improved bioavailability and a more consistent release of the active ingredients. Transdermal supplements are used for various purposes, including hormone replacement, muscle growth, fat loss, and overall performance enhancement.

Mechanism of action

Transdermal prohormones are substances that are applied to the skin and then converted into hormones in the body. They can help increase muscle mass, strength, and overall performance by boosting hormone levels.

Popular Transdermal Prohormones

Some common transdermal prohormones include:

1. 1-Androsterone: 1 AD converts to the hormone 1-testosterone, which can increase muscle mass and strength without water retention. This compound has a higher anabolic ratio in comparison to 4 AD prohormones.
2. 4-Androsterone: 4-Andro or 4 AD supplements convert to testosterone, promoting muscle growth and enhancing overall performance. This works most similarly to testosterone topical gels.
3. Epiandrosterone: Converts to dihydrotestosterone (DHT) which is more androgenic in nature, promoting strength gains and fat loss.

Benefits and Potential Side Effects

Transdermal prohormones offer several benefits, such as increased muscle mass, strength, and improved athletic performance. However, they can also cause side effects like acne, hair loss, and increased aggression. It's important to consult with a healthcare professional before using these substances.

Legal Status and Regulation

The legal status of transdermal prohormones varies by country. Some countries have banned them, while others regulate them as dietary supplements. Always check your country's regulations before purchasing or using transdermal prohormones.

Natural anabolics are plant-derived compounds that can help increase muscle growth, strength, and performance. Unlike prohormones, they don't convert into hormones in the body.

Some common natural anabolics include:

1. Laxogenin: A plant-based compound that can increase protein synthesis, leading to muscle growth and faster recovery.
2. Epicatechin: Found in cocoa, this compound can help reduce muscle breakdown and promote muscle growth.
3. Ursolic Acid: Ursolic Acid: A compound found in apple peels and rosemary that helps support muscle growth, fat loss, and overall body composition.

Benefits and potential side effects

Natural anabolics offer several benefits, such as increased muscle growth, strength, and improved athletic performance. They typically have far fewer risks of side effects than prohormones, making them a safer option for most people.

Legal status and regulation

Natural anabolics are generally considered safe and legal in most countries. However, it's still essential to check your country's regulations before purchasing or using these substances.

Types of transdermal delivery systems

Transdermal delivery systems help administer substances through the skin. Two popular types include:

1. Patches: Adhesive patches that release the substance slowly into the skin.
2. Gels and creams: Topical products that are applied directly to the skin.

Advantages of transdermal delivery

Transdermal delivery offers several advantages, such as:

1. Improved bioavailability: The substance is absorbed directly into the bloodstream, increasing its effectiveness.
2. Controlled release: The substance is released slowly, maintaining stable levels in the body.
3. Bypassing the first-pass metabolism: The substance doesn't pass through the liver, reducing the risk of side effects.

Limitations and Challenges

Transdermal delivery also has some limitations and challenges, including:

1. Skin irritation: Some people may experience skin irritation or allergies to the ingredients in the transdermal product.
2. Limited absorption: Not all substances can be effectively absorbed through the skin.
3. Variable absorption rates: Individual differences in skin thickness and composition can lead to varying absorption rates.

To properly use Transdermal supplements, follow these general guidelines:

1. Clean the skin: Before application, clean and dry the skin to ensure proper absorption. Shaving body hair is recommended but not required.
2. Apply the recommended dosage: Follow the manufacturer's instructions for the correct dosage and application method, which can vary depending on the specific product. Only apply the product to clean dry skin and allow 4-5 minutes to dry before putting on clothing. Best time to apply is in the morning after a shower. Avoid swimming, bathing, or tanning for a few hours after application.
3. Choose the right application site: Apply the prohormone to an area with thin skin and good blood flow, such as the inner arms, upper back, shoulders, and upper chest. Avoid areas with thick skin or excessive hair.
4. Wash your hands: Avoid touching your face as it can cause irritation if rubbed into eyes. Wash your hands thoroughly with soap and avoid allowing women and young children to make contact with the application areas.
5. Cycle the supplements: Follow the suggested cycle lengths of 4 to 6 weeks for transdermal estrogen blockers, 4 to 8 weeks for transdermal fat burners, and 6 to 8 weeks for transdermal prohormones.

Effectiveness

Both transdermal prohormones and natural anabolics can be effective in promoting muscle growth and improving athletic performance. The results depend on the individual and the specific substance used. Prohormones tend to provide faster results however the results provided by them can be trickier to maintain when coming off. Requiring users to follow a proper PCT protocol and run a natural anabolic during their off cycle phase to best maintain results and aid in continued progress.

Safety profile

Natural anabolics generally are generally much safer than transdermal prohormones, with far fewer potential risks of side effects. However, it's crucial to consult with a healthcare professional before using either type of substance.

Cycling is an essential part of using transdermal supplements to ensure their effectiveness, minimize side effects, and allow the body to recover. Here, we will discuss cycling procedures for transdermal prohormones, estrogen blockers, fat loss supplements, and natural anabolics.

Transdermal Prohormones

1. On-cycle: Use the recommended dosage of the prohormone for 6 to 8 weeks. The specific duration depends on the prohormone, your experience, and goals.
2. Off-cycle: After completing the on-cycle phase, start your PCT. After completing your PCT, take a break for the same duration as the on-cycle phase (6 to 8 weeks) to allow your body to recover and restore its natural hormone balance.

Transdermal Estrogen Blockers

Estrogen blockers can be used during the cycle or during the off-cycle phase after completing your PCT to manage potential side effects related to elevated or rebounding estrogen levels.

1. On-cycle estrogen blockers: Start using on cycle estrogen blockers from the start of week 3 of your prohormone cycle and onwards until the end of the cycle. Follow the suggested dosage for 4 to 6 weeks.
2. Off-cycle estrogen blockers: After the PCT phase of your cycle, run the estrogen blocker for 2 to 4 weeks to help prevent any rebounds.

Transdermal Fat Loss Supplements

1. On-cycle: Follow the directed dosage for 4 to 8 weeks depending on your goals and the specific product's instructions.
2. Cycling off: After completing the on-cycle phase, take a break for 4 to 8 weeks to allow your body to recover and avoid developing a tolerance to the supplement.

Transdermal Natural Anabolics (Laxogenin)

1. On-cycle: Use the directed dosage of the specific laxogenin topical supplement for 8 to 12 weeks to maximize its muscle-building effects.
2. Off-cycle: After completing the on-cycle phase, take a break for 4 to 6 weeks to allow your body to recover and to avoid building up a tolerance to the active ingredients in the supplement.

Please note that these cycling procedures are general guidelines. Consult a healthcare professional or a qualified coach before starting any supplement regimen, and always follow the specific instructions provided by the product manufacturer.

Combining Transdermal Prohormones and Natural Anabolics

Some individuals choose to "stack" or combine transdermal prohormones with natural anabolics to achieve synergistic effects and improve overall results.

Stacking Principles and Strategies

When stacking, consider the following principles:

1. Choose complementary substances: Combine substances with different mechanisms of action to maximize benefits.
2. Start with lower doses: Begin with lower doses of each substance to minimize the risk of side effects.
3. Monitor progress and adjust as needed: Keep track of your results and adjust the dosages or combinations as needed to achieve your desired goals.

Potential Benefits and Risks

Stacking transdermal prohormones and natural anabolics can provide enhanced results, such as increased muscle growth, strength, and improved athletic performance. However, combining these substances may also increase the risk of side effects. Always consult a healthcare professional before starting a stacking regimen.

Proper dosage and application

Follow the directed dosages and application instructions for each substance. Overdosing or improper application can lead to side effects and decreased effectiveness.

Precautions and contraindications

Consult a healthcare professional before using transdermal prohormones or natural anabolics, especially if you have pre-existing medical conditions, are taking medications, or are pregnant or nursing.

Monitoring progress and adjusting as needed

Regularly monitor your progress and adjust your dosages or combinations as needed to achieve your desired results. If you experience adverse side effects, stop using the substances immediately and consult a healthcare professional.

It's essential to be aware of potential side effects of testosterone gels and transdermal supplements. Side effects can vary depending on the specific supplement used, dosage, cycle duration, and various individual factors. Here, we will discuss the possible side effects associated with the transdermal supplements mentioned earlier in the article.

Transdermal Prohormones

Some potential side effects of transdermal prohormones include:

1. Acne and oily skin
2. Hair loss
3. Increased aggression and mood swings
4. Elevated blood pressure
5. Hormonal imbalances, such as increased estrogen levels

Transdermal Estrogen Blockers

Possible side effects of transdermal estrogen blockers may include:

1. Joint pain and stiffness
2. Decreased libido
3. Fatigue
4. Headaches
5. Mood swings

Transdermal Fat Loss Supplements

Potential side effects of transdermal fat loss supplements containing 7-Keto and Ursa Major may include:

1. Skin irritation and redness at the application site
2. Insomnia or sleep disturbances
3. Increased heart rate
4. Nausea
5. Headaches

Transdermal Natural Anabolics

Natural anabolics generally have fewer side effects than prohormones. However, some potential side effects may include:

1. Mild gastrointestinal discomfort
2. Headaches
3. Skin irritation at the application site

Discontinue use and call your doctor immediately if you experience any serious adverse reactions while using any transdermal supplements.